Approximately 1.6% of adults in the U.S. suffer from Borderline Personality Disorder (BPD), a condition characterized by difficulty regulating emotions, impulsivity, low self-image, and problems creating and maintaining personal relationships
When you ingest CBD, you ingest certain plant-derived cannabinoids, which act like the endocannabinoids your body produces naturally. The Endocannabinoid System (ECS)produces endocannabinoids to regulate the body’s internal functions and control how we think, feel, and react to things happening in the world around us.
Endocannabinoids do not follow what is considered the typical path of a chemical synaptic signaling, which is for a neurotransmitter to flow from a presynaptic neuron to a postsynaptic neuron and bind to a specific receptor. Instead, endocannabinoids flow backward from postsynaptic neurons to presynaptic neurons in a process called retrograde inhibition.
Endocannabinoids are sent throughout the body by the ECS to achieve and maintain the body’s internal homeostasis, or balance, among all of is working parts. In many psychiatric disorders, symptomatic or episodic behaviors can be traced back to overactive neurons, which send too many neurotransmitters from presynapse to postsynapse and overload receptors.
One of the endocannabinoid receptors that CBD activates are 5-HT1A serotonin receptors. Serotonin, informally known as the “happy chemical,” is a chemical the body produces that’s important for mood regulation. People suffering from depression and anxiety, for instance, seem to exhibit lower levels of serotonin that do people who are not. People with BPD exhibit the same lowered serotonin levels. When CBD activates the 5-HT1A serotonin receptors, they bind to 5-HT serotonin neurotransmitters and increase serotonin production, which in turn combats the negative effects of depression and anxiety that come along with BPD.